SHH-Combo Series Automatic Vial and Ampoule Combo Filling Production line

SHH-Combo Series Automatic Vial and Ampoule Combo Filling Production line

Description:

SHH-Combi Series Automatic Vial and Ampoule Combo Filling Production line 

The SHH-Combo ampoule and vial injection combo washing- dryingfilling-closing production line is composed of the SHH-QCL series vertical ultrasonic washing machine, SHH-SMR series depyrogenation tunnel, SHH-GF series ampoule and vial filling machine, and SHH-GL series capping machine whilst the four machines can also be used independently. Suitable for production of ampoule injection of 1-20ml and vial injection of 2-30ml, it can complete more than 20 work procedures suchas ultrasonic bathing, three-time WFI and recycled water washing, three-time compressed air flushing, exterior wall water washing and compressed air flushing, preheating, drying, sterilizing, depyrogenation, cooling, pre-fill gas purging, filling, post-fill gas purging, sealing, stoppering and capping. Launched successfully after our years of R&D efforts, this combo filling production lineis of high capacity and complied with cGMP requirement. It is featured by fast production, high qualification rate and convenient maintenance and operation, and low running costs. This compact combo filling line adopts the PLC control to achieve full automation.

Performance Features: 

◆ The washing machine adopts mechanical arms to clamp the containers, suitable for ampoules of 1-20ml and vials of 2-30ml;

◆ The water-gas spray nozzles adopt the reciprocating tracking insertion mode for container washing, featured by excellent washing effect and energy saving. It is also provided with a device that prevents the nozzle holder from shaking to enhance the accuracy of the spray nozzle's insertion into the container and reduce the occurrence of nozzle breakage;

◆ The water and gas pipes are totally separable from the spray nozzles, so that cross contamination is avoided and cGMP requirements are met;

◆ The spray nozzle guide mouth of the container washing machine adopts imported ceramic bushing without wear;

◆ Container out-feed is realized by the integral imported synchronous belt that is connected to the container pushing block to convey ampoules, a structure that ensures stable and reliable operation;

◆ The depyrogenation tunnel adopts the hot air circulation heating method with even temperature and energy saving;

◆ The depyrogenation tunnel mesh belt can be equipped with the ultrasonic and CIP cleaning systems;

◆ The depyrogenation tunnel chamber can be subject to all-round, multi-angle high pressure water washing;

◆ The filling and closing machine can be used for ampoule filling, vial filling and full-stoppering, and vial filling and half-stoppering;

◆ The filling and closing machine is provided with sufficient gas purging work stations to ensure one-off purging and the completion of the procedures of pre and post fill nitrogen purging and full/half stoppering;

◆ The filling and closing machine is provided with the functions of no bottle no filling and no bottle no stoppering;

◆ The filling machine can be equipped with the servo filling system; According to customers requirements, the production line can also be equipped with the following options:

◆ Control system of such brands as Siemens, Schneider, Mitsubishi, Allen Bradley, Delta and etc.;

◆ Online monitoring system for water pressure, air pressure, water temperature, ultrasonic strength, dust particles and air speed, alarm, recording and printing systems;

◆ ORABS, CRABS, aseptic isolator system.

◆ The depyrogenation tunnel is provided with the function of protecting against sudden power-off to ensure safe running;

◆ The depyrogenation tunnel can be equipped with the water cooling device that does not consume air volume in the room, whilst reducing the risk of unbalanced differential pressure in the room and achieving good cooling effect;

◆ The depyrogenation tunnel can be equipped with the differential pressure automatic balancing and regulating system to reduce the problems of deviation at the high temperature section caused by unbalanced differential pressure in the room and tunnel, temperature rise in the filling room and washing-drying room;

◆ The depyrogenation tunnel is provided with PAO inspection ports (including inspection ports for air pressure, air speed and dust particles);

◆ The cooling section in the tunnel is provided with the sterilization function (specially chosen by FDA).

Main Technical Parameters

Details: